Postdoctoral Research Associate in Biocatalysis and Enzyme Engineering, University College Dublin

Applications are invited for an 18 month Science Foundation Ireland (SFI) funded Postdoctoral Research Fellow to work under the supervision of Dr Elaine O’Reilly within the School of Chemistry University College Dublin (UCD), Ireland.

The project will focus on developing a biocatalytic route for the synthesis of valuable iminosugars with therapeutic properties. The research aims to construct an artificial enzyme cascade that will enable the conversion of simple building blocks in to high-value products. Development of the approach will involve working with academic and industrial partners to select suitable enzymes, which will be optimised by directed evolution and/or rational design. This is an exciting opportunity to work in a multi-disciplinary environment and develop skills in molecular biology, biocatalysis and synthetic chemistry. 

The project will involve:

  • Subject selected genes/enzymes to rounds of directed evolution and rational redesign 
  • Synthesise necessary substrates and screening tools 
  • Develop high-throughput screening approaches to simplify engineering 

Applicants should have a PhD in Chemistry, Chemical Biology or a closely related area. 
For informal inquiries and discussions, please contact See Group Website for more information:

Fixed Salary: ‚ā¨38,631 per annum

Closing date:  17:00hrs (local Irish time) on the 29th of June 2021.

Applications must be submitted by the closing date and time specified. Any applications which are still in progress at the closing time of 17:00hrs (Local Irish Time) on the specified closing date will be cancelled automatically by the system. UCD are unable to accept late applications.

Prior to application, further information (including application procedure) should be obtained from the Work at UCD website:

Please apply here: 

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