We are looking for a highly motivated post-doc to work on a project at the chemistry-biology interface looking to improve the sustainability of chemical synthesis. The project seeks to design new metalloenzymes using unnatural amino acids or synthetic cofactors and to apply these catalysts in selective chemical synthesis. Initially these metalloenzymes will be used for in vitrocatalysis, before being applied in biosynthetic cascades with the ultimate goal to use the metalloenzymes in vivo. This exciting project is funded by a UKRI Future Leader Fellowship to Dr Amanda Jarvis at University of Edinburgh.
The position would be best suited to a researcher with an interest in applying protein design to the development of novel catalysts for a sustainable chemical future. A successful candidate is likely to have experience in a number of the following: protein design, biocatalysis, protein production in E.coli and relevant analytical skills for either catalysis or structural characterisation of proteins (e.g. HPLC, GC, NMR, X-ray crystallography). The candidate should have an excellent academic track record (commensurate with their career stage and experience), ideally including peer-reviewed published work. They are expected to be active in developing the project, to collaborate with all team members, and to contribute to the mentoring/training of PhD students and project students. The candidate will benefit from training in the vibrant scientific environment provided by the School of Chemistry in Edinburgh, as well as in the laboratories of our collaborators. More information about the Jarvis group can be found here (www.amandajarvis.ac.uk). Informal enquiries can be made to firstname.lastname@example.org.
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