Deciphering cellular sugar pathways using chemically-controlled carbohydrate probesĀ
All cells use sugar, but a consequence of unbalanced sugar usage is disease through hexosamine sugar biosynthetic pathways. To precisely define the roles of hexosamine sugar-driven effects, we designed chemical tools sensitive for live-cell applications, for example our light-controlled photo-sugars and our cell compartment-specific “GlycoID” biorthogonal labeling strategy. These precisionā¦